
Target Identification for Drug Discovery
Identification of suitable targets is critical for any drug discovery program. However, there is no standardized procedure for target identification in drug discovery. Artificial Intelligence (AI) and machine learning (ML) approaches are increasingly being employed in this process, with the goal of finding clinically effective targets.
BioPrompt has developed an AI-assisted and comprehensive method to identify potential targets by integrating key factors such as disease relevance, target biology, mechanism of action, pathway analysis, potential toxicity, druggability, potential for combination therapy, market interest and competitive landscape. This approach results in a curated list of high-value targets, categorized as follows:
Novel Targets: Innovative, unexplored, with high potential.
Fast Follower Targets: Validated targets with limited market competition.
Suitable for:
Emerging biotech firms and research Institutions aiming to identify high quality targets for initiating drug development programs.
Established companies aiming to expand their pipelines.



Currently Available Targets
Target
Therapeutic Area
Category
BPR-001
Oncology
Immuno-Oncology
BPR-002
BPR-003
A comprehensive project proposal will be available, encompassing disease relevance, target biology, druggability, pathway analysis, hit identification strategies, appropriate screening assays, flow schemes with Go/No-Go decision points, target product profile (TPP) at various stages, target safety evaluation, a detailed SWOT analysis, competitive landscape and market potential.
Oncology
Oncology
Oncology
Epigenetic Pathway
BPR-004
Epigenetic Pathway
DDR Pathway

Assay Development and Screenig for a Wide Range of Target Classes
Kinases
Phosphatases
GTPases
ATPases
Helicases
Phospho-diesterases
Proteases
BioPrompt possesses extensive expertise in assay development for a wide range of target types including enzymes, receptors and scaffolding proteins.
We offer comprehensive assay development and screening support for these targets.
Additional in vitro/ in vivo studies in the preclinical stage can be done through our network of CROs
RNA Modifiers
Exonucleases
Deubiquitinating Enzymes
DNA Repair Enzymes
Nuclear Receptors
GPCRs
Epigenetic Targets
Drug Discovery Targets
Mitochondrial Chaperones
Molecular Motor Proteins
E3 Ligases
PROTAC/Glue Degrader Targets
Immune Checkpoint Proteins
Antibodies
Scaffolding Proteins

Assay Development with a range of Technologies
BioPrompt possesses extensive experience in the development of assays across a broad range of assay technologies.
We offer end-to-end support for assay development, screening and data analysis.
BioPrompt coordinates assays across a range of technologies through a trusted network of CROs and Institutes.
Absorbance
Luminescence
Fluorescence
FRET/TR-FRET
Fluorescence Polarization
Alpha Screen
Surface Plasmon Resonance (SPR)
Thermal Shift Assay
Biolayer Interferometry (BLI)
Microscale Thermophoresis (MST)
Nuclear Magnetic Resonance (NMR)
Mass Spectrometry
Radiometry
ELISA


Assay Technologies

Facilitation of Preclinical Studies
BioPrompt leverages its CRO partnerships to support the following studies.
Different studies can be done at different CROs to optimize cost and service quality.
Ideal for startup and small companies lacking the scientific capabilities to perform all studies in-house.
Solubility
Caco-2/MDCK Permeability
Plasma Protein Binding (PPB)
Metabolic Stability (m/r/d/h)
Hepatocyte Stability
Plasma Stability
CYP Inhibition
Time Dependent Inhibition (TDI)
CYP Induction
PK Profiling (Mouse/Rat)
Maximum Tolerated Dose (MTD)
4/14/28 day Repeated Dose Toxicity
hERG Assay
Genotoxicity Screening
Micronucleus Test
Ames Test
Single Dose Studies
Repeated Dose Studies
Dose-Limiting Toxicity Studies
Dose Escalation Toxicity Studies
Toxicology Studies
ADME/PK

Expert drug discovery and consulting services for biotech firms and Institutes
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Contact Us Tel: +91 98456 80674 Email: contact@bioprompt.in
Consulting Services Targets for Drug Discovery Facilitation of Preclinical Studies
Location NB-3/44, Vijaya Enclave Bilekahalli, Bangalore - 560076 Karnataka, INDIA
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